Amy Chang

Learn More
PURPOSE Polysaccharide krestin (PSK) is a mushroom extract that has been long used in Asia and recently in Western countries as a treatment for cancer due to its presumed immune potentiating effects. Although there have been reports of clinical responses after patients have ingested PSK, the mechanism of action of the agent remains undefined. The current(More)
Multiple TLR agonists have been shown to have antitumor effects in animal models. However, the therapeutic efficacy of TLR agonist monotherapy in cancer treatment has been limited, and the mechanisms of failure remain unknown. We demonstrate that topical treatment with a TLR-7 agonist, imiquimod, can elicit significant regression of spontaneous breast(More)
Stress is present in everyday life in various forms and situations. Two stressors frequently investigated are physiological and psychosocial stress. Besides similar subjective and hormonal responses, it has been suggested that they also share common neural substrates. The current study used activation-likelihood-estimation meta-analysis to test this(More)
S ince publication of the AAAS 1989 report " Science for all Americans " (1), commissions, panels, and working groups have agreed that reform in science education should be founded on " scientific teaching, " in which teaching is approached with the same rigor as science at its best (2). Scientific teaching involves active learning strategies to engage(More)
The complex morphology of axons presents a challenge in understanding axonal responses to injury and disease. By in vivo two-photon imaging of spinal dorsal column sensory axons, we systematically examined the effect of injury location relative to the main bifurcation point on axon degeneration and regeneration following highly localized laser injuries.(More)
I. INTRODUCTION Research and development in undergraduate science, mathematics, engineering, and technology education would probably benefit from more exchange of information among workers in different disciplines. may have something to learn from biologists and vice versa. However, there are evidently no biological counterparts to the physicists' (A)(More)
A number of national reports, including Vision and Change in Undergraduate Biology Education: A Call to Action, have called for drastic changes in how undergraduate biology is taught. To that end, the American Society for Microbiology (ASM) has developed new Curriculum Guidelines for undergraduate microbiology that outline a comprehensive curriculum for any(More)