Amita Kush Mehrotra

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BACKGROUND AND OBJECTIVES Fibromatoses of the extremities are rare and often recalcitrant to treatment. We evaluated the clinical and pathologic features of a group of extremity fibromatoses treated by surgical excision with or without adjuvant therapy to determine if any clinical or pathologic parameters were predictive of clinical outcome. METHODS(More)
Hypoxia limits wound healing. Both normobaric (1 atm) and hyperbaric oxygen (HBO) approaches have been used clinically to oxygenate wound tissue. Recently, we reported that HBO ameliorates stress-induced impairment of dermal healing. We examined the effect of pressure on oxygen-induced vascular endothelial growth factor (VEGF) expression by human HaCaT(More)
Developing gene constructs with the barnase gene and propagating them in Escherichia coli or Agrobacterium tumefaciens is difficult as unintended leaky expression leads to the death of the bacterial cells. In the present work, we circumvented this problem by developing intron containing barnase genes. We tested the use of two different introns viz., (i) the(More)
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