Amit Kumar Pandey

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NOD2, RIP2 and IRF5 Play a Critical Role in the Type I Interferon Response to Mycobacterium tuberculosis

Amit Kumar Pandey, Yibin Yang, +6 authors Michelle A Kelliher
PLoS pathogens
2009

While the recognition of microbial infection often occurs at the cell surface via Toll-like receptors, the cytosol of the cell is also under surveillance for microbial products that breach the cell… (More)

Increased NOD2-mediated recognition of N-glycolyl muramyl dipeptide

François Coulombe, Maziar Divangahi, +8 authors Marcel A. Behr
The Journal of experimental medicine
2009

Peptidoglycan-derived muramyl dipeptide (MDP) activates innate immunity via the host sensor NOD2. Although MDP is N-acetylated in most bacteria, mycobacteria and related Actinomycetes convert their… (More)

Selection of aptamers for aflatoxin M1 and their characterization.

Swadesh Malhotra, Amit Kumar Pandey, Yudhishthir Singh Rajput, Rupanjali B Sharma
Journal of molecular recognition : JMR
2014

In the present work, aptamers against aflatoxin M1 and aflatoxin B1 were generated and tested for creating proof of principle of recognition of aflatoxin M1 by generated aptamers. The aptamers were… (More)

Immobilized aptamer on gold electrode senses trace amount of aflatoxin M1

Amit Kumar Pandey, Yudhishthir Singh Rajput, Rajan Gopal Sharma, Dheer Singh
Applied nanoscience
2017

An electrochemical aptasensor for detection of trace amounts of aflatoxin M1 was developed. This required immobilization of aptamer on screen printed gold electrode comprising of working electrode,… (More)

Rational design of drug-like compounds targeting Mycobacterium marinum MelF protein

Renu Dharra, Sakshi Talwar, +5 authors Promod K Mehta
PloS one
2017

The mycobacterial mel2 locus (mycobacterial enhanced infection locus, Rv1936-1941) is Mycobacterium marinum and M. tuberculosis specific, which can withstand reactive oxygen species (ROS) and… (More)

TIP60-miR-22 axis as a prognostic marker of breast cancer progression.

Amit Kumar Pandey, Yanzhou Zhang, +4 authors Sudhakar Jha
Oncotarget
2015

MicroRNAs (miRNAs) are 22- to 24-nucleotide, small, non-coding RNAs that bind to the 3'UTR of target genes to control gene expression. Consequently, their dysregulation contributes to many diseases,… (More)

Gene Expression Profiling and Network Analysis Reveals Lipid and Steroid Metabolism to Be the Most Favored by TNFα in HepG2 Cells

Amit Kumar Pandey, Neha Munjal, Malabika Datta
PloS one
2010

BACKGROUND The proinflammatory cytokine, TNFalpha, is a crucial mediator of the pathogenesis of several diseases, more so in cases involving the liver wherein it is critical in maintaining liver… (More)

TIP60 represses telomerase expression by inhibiting Sp1 binding to the TERT promoter

Deepa Rajagopalan, Amit Kumar Pandey, +10 authors Sudhakar Jha
PLoS pathogens
2017

HIV1-TAT interactive protein (TIP60) is a haploinsufficient tumor suppressor. However, the potential mechanisms endowing its tumor suppressor ability remain incompletely understood. It plays a vital… (More)

Camel milk ameliorates hyperglycaemia and oxidative damage in type-1 diabetic experimental rats.

Vijay Singh Meena, Yudhishthir Singh Rajput, Amit Kumar Pandey, Rajan Gopal Sharma, Raghvendar Singh
The Journal of dairy research
2016

This study was designed to assess anti-diabetic potential of goat, camel, cow and buffalo milk in streptozotocin (STZ) induced type 1 diabetic albino wistar rats. A total of 48 rats were taken for… (More)

TIP60 inhibits metastasis by ablating DNMT1-SNAIL2-driven epithelial-mesenchymal transition program.

Yanzhou Zhang, Vanitha Krishna Subbaiah, +11 authors Sudhakar Jha
Journal of molecular cell biology
2016

HIV-Tat-interacting protein of 60 kDa (TIP60) is a lysine acetyltransferase and known to be downregulated in multiple cancers. Among various signalling pathways, TIP60 is implicated in regulating… (More)

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