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Recombinant adeno-associated virus (rAAV) is a promising vector for therapy of retinal degenerative diseases. We evaluated the efficiency, cellular specificity, and safety of retinal cell transduction in nonhuman primates after subretinal delivery of an rAAV carrying a cDNA encoding green fluorescent protein (EGFP), rAAV. CMV.EGFP. The treatment results in(More)
The ability to reserve real-time connections in advance is essential in all distributed multi-party applications (i.e., applications involving multiple human beings) using a network that controls admissions to provide good quality of service. This paper discusses the requirements of the clients of an advance reservation service, and a distributed design for(More)
Current approaches to supporting real-time communication allocate network resources either to individual connections, or to aggregates of connections. Resource sharing is a new approach that exploits known relationships between related connections to allow network resources to be shared between them without sacriic-ing well-deened guarantees. We present a(More)
This paper focuses on the investigation of integrated CMOS and Silicon/Germanium (SiGe) devices for high-speed optical receiver circuits. In this paper, we present several competitive designs of front-end transimpedance amplifiers (TIA) for optical receiver applications using the IBM 5HP (0.5micron) SiGe technology. This technology exhibits f T and f MAX of(More)
Most of the web traffic today uses the HyperText Transfer Protocol (HTTP), with Transmission Control Protocol (TCP) as the underlying transport protocol. Unfortunately , TCP is poorly suited for the short conversations that comprise a significant component of web traffic. The overhead of setting up and tearing down TCP state amor-tizes poorly for these(More)
There is considerable interest in the network community in supporting real-time multi-party applications, such as video conferenc-ing. The Tenet Group at UC Berkeley and ICSI has designed and implemented protocols that provide quality of service (QoS) guarantees for real-time traac on packet switching networks. Suite 2 of the Tenet protocols provides(More)