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Alzheimer's disease (AD) is the most common neurodegenerative disease worldwide. Pharmacological treatments presently available can slow down the progression of symptoms but can not cure the disease. Currently there is widening recognition that AD is closely associated with impaired insulin signaling and glucose metabolism in brain, suggesting it to be a(More)
The ability to reserve real-time connections in advance is essential in all distributed multi-party applications (i.e., applications involving multiple human beings) using a network that controls admissions to provide good quality of service. This paper discusses the requirements of the clients of an advance reservation service, and a distributed design for(More)
Neuro-inflammation and oxidative stress plays a key role in the pathophysiology of Parkinson's disease (PD). Studies demonstrated that neuro-inflammation and associated infiltration of inflammatory cells into central nervous system are inhibited by 3-hydroxy-3-methyl glutaryl co-enzyme A (HMG-CoA) reductase inhibitors. Based on these experimental evidences,(More)
Current approaches to supporting real-time communication allocate network resources either to individual connections, or to aggregates of connections. Resource sharing is a new approach that exploits known relationships between related connections to allow network resources to be shared between them without sacriic-ing well-deened guarantees. We present a(More)
Pheochromocytoma is a catecholamine secreting tumor that originate from chromaffin cells. Usually, it is solid neoplasm of the adrenal medulla, however cystic pheochromocytoma is a rare neuro-endocrine tumour that is frequently asymptomatic and often diagnosed incidentally on imaging or intra-operatively. Only a few cases of cystic pheochromocytomas have(More)
This paper focuses on the investigation of integrated CMOS and Silicon/Germanium (SiGe) devices for high-speed optical receiver circuits. In this paper, we present several competitive designs of front-end transimpedance amplifiers (TIA) for optical receiver applications using the IBM 5HP (0.5micron) SiGe technology. This technology exhibits f T and f MAX of(More)
While several recent reports have described the toxicity of water-soluble C60 fullerene nanoparticles, none have reported the toxicity resulting from the inhalation exposures to C60 fullerene nanoparticles or microparticles. To address this knowledge gap, we exposed male rats to C60 fullerene nanoparticles (2.22 mg/m3, 55 nm diameter) and microparticles(More)