Amirhossien Hakamivala

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Controlled delivery of signaling factors could be a great approach in the tissue engineering field. Nano-niosomal drug delivery systems offer numerous advantages for this purpose. The present study reports the formulation and evaluation of a growth factor (GF)-loaded nano-niosome-hydrogel composite for GF delivery to modulate cell behavior. Niosomes were(More)
Silibinin is a natural flavonoid with a strong antioxidant property and weak cytotoxic activity. It has demonstrated anti-tumoural activity against many types of malignancies; however, due to its hydrophobic structure, it has poor water solubility, bioavailability and permeability across intestinal epithelial cells. To improve the effect of silibinin, we(More)
This study reports the development of a highly stable niosomal nanostructure based on Span 60/cholesterol (CH)/N-trimethyl chitosan (TMC) system and its potential application for oral delivery of insulin. Insulin loaded niosomes were prepared by reversed-phase evaporation and TMC coating was performed by incubation of niosomal suspensions with TMC solution.(More)
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