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Leptospira interrogans, a Gram-negative bacterial pathogen is the main cause of human leptospirosis. Lipid A is a highly immunoreactive endotoxic center of lipopolysaccharide (LPS) that anchors LPS(More)
Infective endocarditis (IE) has emerged as a public health problem due to changes in the etiologic spectrum and due to involvement of resistant bacterial strains with increased virulence. Developing(More)
197 Combination of e-pharmacophore modeling, multiple docking strategies and molecular dynamic simulations to discover of novel antagonists of BACE1 Natarajan Pradeep, Manne Munikumar, Sandeep(More)
A series of acyl hydrazone derivatives were synthesized and screened for antiinflammatory and analgesic activities. The N-acylarylhydrazone compounds described herein were designed by combining the(More)