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In this work we consider a criterion for selecting temperature intervals in parallel-tempering molecular simulations. Parallel tempering ͑or replica exchange͒ is a technique used to enhance the sampling of configurations. 1 The primary aim is to enable systems being simulated at low temperatures to overcome energetic barriers that hinder their sampling and(More)
We previously reported that sterol-regulatory-element-binding-protein-1c (SREBP-1c) mediates insulin upregulation of genes encoding glycolytic and lipogenic enzymes in rat skeletal muscle. Here, we assessed whether glucose could regulate gene expression in contracting myotubes deriving from cultured muscle satellite cells. Glucose uptake increased twofold(More)
Subpopulations of very primitive hematopoietic cells were isolated by fluorescence-activated cell sorter (FACS) selection of density gradient-enriched, lineage-depleted marrow cells with blast cell light scatter characteristics that bound low levels of the DNA binding dye, Hoechst 33342 (Hö) and retained differential amounts of the mitochondrial binding(More)
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