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  • Güzin Surat, William A Wallace, Ian F. Laurenson, Amie-Louise Seagar
  • Medicine
  • Journal of clinical pathology
  • 2014 (First Published: 1 December 2014)
  • AIMS To investigate the diagnostic accuracy of IS6110 real-time PCR for detection of Mycobacterium tuberculosis complex (MTBC) in DNA extracted from formalin-fixed paraffin embedded (FFPE) tissuesContinue Reading
  • Benjamin J. Parcell, Anna A Jarchow-MacDonald, Amie-Louise Seagar, Ian F. Laurenson, Gordon J. Prescott, Michael Lockhart
  • Medicine
  • The Journal of infection
  • 2017 (First Published: 1 May 2017)
  • OBJECTIVES Xpert MTB/RIF (Cepheid) is a rapid molecular assay shown to be sensitive and specific for pulmonary tuberculosis (TB) diagnosis in highly endemic countries. We evaluated its diagnosticContinue Reading
  • Amie-Louise Seagar, Barry Neish, Ian F. Laurenson
  • Biology, Medicine
  • Journal of medical microbiology
  • 2012 (First Published: 1 October 2012)
  • An in-house IS6110 real-time PCR (IH IS6110), MTB Q-PCR Alert (Q-PCR) and GenoType MTBDRplus (MTBDR; Hain Lifescience) were compared for the direct detection of Mycobacterium tuberculosis complexContinue Reading
  • Dalal S. Al-Rubaye, Grace Henihan, +7 authors Till T. Bachmann
  • Biology, Medicine
  • Journal of medical microbiology
  • 2016 (First Published: 1 February 2016)
  • We report on a molecular investigation carried out to ascertain the prevalence of drug-resistant tuberculosis (TB) and the specific gene mutations responsible for resistance to rifampicin (RIF)Continue Reading