Ameziane Cherfouh

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Chromosomal mapping of genes linked with 19 measures of sensorial, motor, and body weight development were investigated. Chromosomal mapping is the first step towards gene identification. When a genomic region is shown to be linked to a trait, it is possible to select a reduced number of candidate genes that have been previously mapped on this region. The(More)
Down syndrome occurs every 1/1000 births and is the most frequent genetic cause of mental retardation. The genetic substrate of Down syndrome, an extra chromosome 21, was discovered by Lejeune, half-a-century ago, and the chromosome has been fully sequenced, although the gene(s) implicated in the mental retardation observed with the syndrome are still(More)
Phenotypic differences among mice with disrupted genes and those with wild-type alleles have not provided the necessary evidence for desired gene/phenotype correlations. These differences could be due to "passenger genes" from the donor 129 strains that are used to produce stem cells. Three variations of attack behavior were measured, using mice carrying a(More)
The Galois Lattice of a binary relation formalizes it as a concept system, dually ordered in "extension" / "intension". All implications between conjunctions of properties holding in it are summarized by a (recursive) canonical basis -all basis having the same cardinality (see [MR #87k:08009]). We report here how these tools structure phenotypes / genotypes(More)
The first aim of the study was to compare developmental trends in the degree of laterality (independent of direction) observed in two handedness tasks. The second aim was to assess family resemblance in the degree of laterality using the same two tasks. The sample was comprised of 186 left-handers and 302 right-handers aged from 6 to 66. Some of the sample(More)
A previous paper assessed a "Molecular Mapping of Twenty-Four Features of Down Syndrome on Chromosome 21" (Delabar et al., 1993), by analyzing the genotypes/phenotypes of patients suffering from partial trisomy. The mapping was defined through implications--each feature was mapped to the conjunction of cytogenetic bands that were shared by all patients(More)
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