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When J. Powell (Biochem. J. 54:210, 1953) established dipicolinic acid (DPA) as an important constituent of bacterial spores, microbiologists became concerned about the function this compound serves and about its biosynthetic pathway. It is now generally considered that DPA is involved in the heat resistance of spores, but the mechanism is unknown. A number(More)
Human hookworm infection is a major cause of anemia and malnutrition in the developing world. In an effort to control hookworm infection, the Human Hookworm Vaccine Initiative has identified candidate vaccine antigens from the infective larval stage (L3) of the parasite, including a family of pathogenesis-related-1 (PR-1) proteins known as the(More)
Gene transfer vectors encoding two or more genes are potentially powerful research tools and are poised to play an increasingly important role in gene therapy applications. Common strategies employed to express more than one transgene per vector include the use of multiple promoters, internal ribosome entry site (IRES) elements, splicing signals and fusion(More)
Crystallization and preliminary X-ray analysis of Na-ASP-1, a multi-domain pathogenesis-related-1 protein from the human hookworm parasite Necator americanus. Corrigendum. Data collection and instrument information reported in the article by Asojo et al. In the article by Asojo et al. (2005), the X-ray detector and data collection were reported incorrectly(More)
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