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Databases often give incorrect answers when data are missing or semantic understanding of the data is required. Processing such queries requires human input for providing the missing information, for performing computationally difficult functions, and for matching, ranking, or aggregating results based on fuzzy criteria. In this demo we present CrowdDB, a(More)
CXCR4 plays a crucial role in the inflammatory disease process, providing an attractive means for drug targeting. A series of novel amide-sulfamide derivatives were designed, synthesized and comprehensively evaluated. This new scaffold exhibited much more potent CXCR4 inhibitory activity, with more than 70% of the compounds showed notably better binding(More)
CXCR4 plays a crucial role in recruitment of inflammatory cells to inflammation sites at the beginning of the disease process. Modulating CXCR4 functions presents a new avenue for anti-inflammatory strategies. However, using CXCR4 antagonists for a long term usage presents potential serious side effect due to their stem cell mobilizing property. We have(More)
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