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Databases often give incorrect answers when data are missing or semantic understanding of the data is required. Processing such queries requires human input for providing the missing information , for performing computationally difficult functions, and for matching, ranking, or aggregating results based on fuzzy criteria. In this demo we present CrowdDB, a(More)
CXCR4 plays a crucial role in the inflammatory disease process, providing an attractive means for drug targeting. A series of novel amide-sulfamide derivatives were designed, synthesized and comprehensively evaluated. This new scaffold exhibited much more potent CXCR4 inhibitory activity, with more than 70% of the compounds showed notably better binding(More)
CXCR4 plays a crucial role in recruitment of inflammatory cells to inflammation sites at the beginning of the disease process. Modulating CXCR4 functions presents a new avenue for anti-inflammatory strategies. However, using CXCR4 antagonists for a long term usage presents potential serious side effect due to their stem cell mobilizing property. We have(More)
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