Amar Das Gupta

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CONTEXT Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired clonal stem cell disorder characterized by complement-mediated hemolysis due to reduced expression of glycosyl phosphatidylinositol-anchored complement deactivating proteins such as CD55 and CD59 on RBC. Flow cytometric analysis of CD55 and CD59 expression by RBC is a reliable tool for the(More)
Hepatosplenic T-cell lymphomas (HSTCL) are rare cancers and comprise 5% of peripheral T-cell lymphomas. These well-characterized extranodal lymphomas have a disguised onset, secondary to intrasinusoidal infiltration of the spleen, liver, and bone marrow, with a rapidly progressive course that is poorly responsive to chemotherapy and often ensues in the(More)
BACKGROUND Alpha globin chain variants are clinically significant since they directly influence the structure and function of the hemoglobin (Hb) molecules they constitute, either in combination with normal beta globin chains or with variant beta chains, thereby altering the morbidity and mortality associated with the resultant hemoglobinopathies. We(More)
Infectious mononucleosis is characterized by an intensive lymphoproliferation with atypical forms which sometimes resemble with acute leukemia or malignant lymphoproliferative diseases. Flow cytometric analysis of lymphocytes shows a typical phenotype but unawareness of it may lead to misdiagnosis of malignant lymphoproliferative diseases. Herewith we(More)
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