Amani Shatnawi

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Estradiol (E2) acts through the estrogen receptor (ER) to downregulate many genes, and tamoxifen (Tam) largely reverses this repression but the underlying mechanisms are unclear. Repression of the folate receptor (FR)-alpha P4 core promoter by ER is enhanced by E2 and reversed by Tam. This effect was unaffected by inhibition of new protein synthesis and(More)
The androgen receptor (AR) has a critical role in the development and progression of prostate cancer (PC) and is a major therapeutic target in this disease. The transcriptional activity of AR is modulated by the coregulators with which it interacts, and consequently deregulation of cofactor expression and/or activity impacts the expression of genes whose(More)
This paper presents a new hashing algorithm in discovering association rules among large data itemsets. Our approach scans the database once utilizing an enhanced version of priori algorithm, Direct Hashing and Pruning algorithm (DHP). The algorithm computes the frequency of each k-itemsets and discovers set of rules from frequent k-itemsets. Once the(More)
Nuclear expression of CCAAT enhancer binding protein-alpha (C/EBPalpha), which supports tissue differentiation through several antiproliferative protein-protein interactions, augurs terminal differentiation of prostate epithelial cells. C/EBPalpha is also a tumor suppressor, but in many tumors its antiproliferative interactions may be attenuated by(More)
Haematol 1997; 99: 84–92. 3 Annino L, Vegna ML, Camera A, Specchia G, Visan G, Fioritoni G et al. Treatment of adult acute lymphoblastic leukemia (ALL): longterm follow-up of the GIMEMA ALL 0288 randomized study. Blood 2002; 99: 863–871. 4 Faderl S, Jeha S, Kantarjian HM. The biology and therapy of adult acute lymphoblastic leukemia. Cancer 2003; 98:(More)
Technology innovation has led to an explosive growth of recorded information, with the Web being a huge repository under no editorial control. Providing with people with access to information is not the problem; the problem is that people with varying needs and preferences navigate through large Web structures, missing the goal of their inquiry. Web usage(More)
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