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Overexpression of the MRE11-RAD50-NBS1 (MRN) complex in rectal cancer correlates with poor response to neoadjuvant radiotherapy and prognosis
TLDR
Expression levels of MRN complex proteins significantly predict disease-free survival in rectal cancer patients, including those treated with neoadjuvant radiotherapy, and may have value in the management of these patients. Expand
Early Postoperative Low Expression of RAD50 in Rectal Cancer Patients Associates with Disease-Free Survival
Background: Molecular biomarkers have the potential to predict response to the treatment of rectal cancer. In this study, we aimed to evaluate the prognostic and clinicopathological implication ofExpand
Aberrant Expression of RAD52, Its Prognostic Impact in Rectal Cancer and Association with Poor Survival of Patients
TLDR
It is suggested that RAD52 may have clinical value as a prognostic marker of tumour response to neoadjuvant radiation and both disease-free status and overall survival in patients with rectal cancer. Expand
The Genomic Landscape of Thyroid Cancer Tumourigenesis and Implications for Immunotherapy
TLDR
This review provides a summary of the recent genetic aberrations implicated in the development and progression of thyroid cancer and implications for immunotherapy. Expand
Primary cavernous haemangioma of the thyroid: a rare pathology
TLDR
A 77-year-old female referred with a 1-year history of an acquired, enlarging neck mass was considered high risk due to a short superior thyroid artery stump and moderate carotid artery stenosis and underwent a right hemi-thyroidectomy without complication. Expand
Zosteriform cutaneous metastases: an unusual presentation of metastatic lung carcinoma
TLDR
The case of a 78‐year‐old gentleman with a background of end‐stage renal disease with metastatic adenocarcinoma of the lung which was diagnosed due to the development of zosteriform cutaneous metastases around his vascular catheter (vascath) site is discussed. Expand
Cancer-associated fibroblasts (CAFs) in thyroid papillary carcinoma: molecular networks and interactions
TLDR
This review summarises the clinical presentation of current knowledge of classical papillary thyroid carcinoma (PTC), emerging molecular diagnostics and future directions of classical PTC research. Expand