Amanda M Glass

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Nickel superoxide dismutase (Ni-SOD) catalyzes the disproportionation of superoxide to molecular oxygen and hydrogen peroxide, but the overall reaction mechanism has yet to be determined. Peptide-based models of the 2N:2S nickel coordination sphere of Ni-SOD have provided some insight into the mechanism of this enzyme. Here we show that the coordination(More)
The metal abstraction peptide (MAP) tag is a tripeptide sequence capable of abstracting a metal ion from a chelator and binding it with extremely high affinity at neutral pH. Initial studies on the nickel-bound form of the complex demonstrate that the tripeptide asparagine-cysteine-cysteine (NCC) binds metal with 2N:2S, square planar geometry and behaves as(More)
The unique metal abstracting peptide asparagine-cysteine-cysteine (NCC) binds nickel in a square planar 2N:2S geometry and acts as a mimic of the enzyme nickel superoxide dismutase (Ni-SOD). The Ni-NCC tripeptide complex undergoes rapid, site-specific chiral inversion to dld-NCC in the presence of oxygen. Superoxide scavenging activity increases(More)
The optical transmission spectrum of a discontinuous metal-island film is strongly affected by extremely thin layers (<1 monolayer) of dye adsorbate. Experimentally observed splitting and broadening of the plasma resonance of silver films with adsorbed rhodamine B and nile blue dyes can be described by an effective-medium calculation for the optical(More)
By using an evaporated silver film that has a continuously varying thickness, we have demonstrated the dependence of surface-enhanced Raman scattering (SERS) on the dielectric properties of the film. These results support local field models that are based on metal-particle resonances for SERS.
Measurements and theoretical calculations are presented for the photorefractive effect in three semi-insulating semiconductors (GaAs:EL2, InP:Fe, and CdTe:V) using 29-psec pulses at a wavelength of 1.06 microm. The photorefractive gain is largest in the CdTe crystal and smallest in our InP sample. The major differences between the materials responsible for(More)
Volume holographic gratings are written with ultraviolet light in high-optical-quality, commercially available Ge-doped silica films and in Ge-doped optical-fiber preform sections loaded with molecular hydrogen. In the film samples, peak refractive-index changes exceeding 10(-2) and a sensitivity (index change/absorbed energy density) of 0.4 × 10(-7)(More)
Single-pulse and cw measurements of the response of a semi-insulating CdZnTe/ZnTe multiple-quantum-well photorefractive device are presented. In single-pulse experiments, photodiffractive (absorption) gratings have been written with less than 1.8-microJ/cm(2) incident fluence, and a diffraction efficiency of 1.1% is obtained from the 1.56-microm active(More)