Amanda H Bell

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During surfactant treatment of respiratory distress syndrome, 23 premature newborns were investigated with continuous amplitude-integrated electroencephalography (cerebral function monitors). Simultaneously, arterial blood pressure and transcutaneous blood gas values were recorded. A short (less than 10 minutes) but significant decrease in cerebral activity(More)
OBJECTIVES To determine the clinical significance of subnormal serum vitamin B12 concentration in older people by comparing the hematological, neurological, and biochemical findings in patients with subnormal serum B12 with a control group with normal B12 levels. DESIGN Clinical and laboratory assessment of hospital patients selected to represent a wide(More)
Trophic dynamics (community composition and feeding relationships) have been identified as important drivers of methylmercury (MeHg) bioaccumulation in lakes, reservoirs, and marine ecosystems. The relative importance of trophic dynamics and geochemical controls on MeHg bioaccumulation in streams, however, remains poorly characterized. MeHg bioaccumulation(More)
Continuously recorded amplitude-integrated EEG (aEEG) traces of 77 preterm babies were analysed retrospectively, to study the effect of different sedative drugs over a 24-h period. Thirty-seven babies were treated with phenobarbitone, 18 received morphine and 22 babies received no regular sedation. A "burst" was defined as a discharge of integrated(More)
We have used two main techniques to investigate the effect of surfactant therapy on the cerebral circulation in 34 babies. Twenty-one babies were studied using near infrared spectroscopy and 13 had cerebral blood flow measured using a xenon clearance technique. Other measures recorded included amplitude integrated EEG, mean arterial blood pressure and(More)
We have previously reported reduction in EEG activity in preterm babies after tracheal instillation of Curosurf. To elucidate the cause of EEG depression, we have examined cerebral blood flow (CFB), amplitude-integrated EEG (aEEG), mean arterial blood pressure (MABP) and plasma hypoxanthine (Hx) concentration in a group of preterm babies before and(More)
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