Amanda Guerra Morais Rego Sousa

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BACKGROUND The aim of this study was investigate the relationship between ABCB1 and ABCC3 gene expressions in peripheral blood cells (PBC) and the response to clopidogrel in patients with coronary arterial disease (CAD). METHODS Twenty-six male CAD patients (50-70 years) under treatment with clopidogrel (75 mg/day) for at least 5 days were selected. Blood(More)
OBJECTIVE To verify the influence of moderate- or high-pressure balloon inflation during primary coronary stent implantation for acute myocardial infarction. METHODS After successful coronary stent implantation, 82 patients were divided into 2 groups according to the last balloon inflation pressure: group 1 (> or = 12 to < 16 atm) and group 2 (> or = 16(More)
BACKGROUND To investigate genes differentially expressed in peripheral blood cells (PBCs) from patients with coronary arterial disease (CAD) under double anti-platelet therapy. METHODS Twenty-six CAD patients that were submitted to percutaneous coronary intervention (PCI) were selected to participate in this study. These patients took 100mg/day of(More)
OBJECTIVE Iliac vein stenting has emerged as the procedure of choice in the treatment of iliac vein obstruction (IVO). However, clinical outcomes have never been studied by a randomized clinical trial. Our purpose was to compare medical and endovascular treatment results in symptomatic chronic venous disease (CVD) patients with significant IVO documented by(More)
Individuals with moderate angiographic lesions (vascular lumen obstruction between 40 and 70%) account for a significant number of patients in our daily practice. However, the choice of a criterion that may differentiate the patients who should from those who should not undergo coronary revascularization procedures is yet to be established. In that subgroup(More)
C ontrast-induced acute kidney injury is defined as a sudden decline in kidney function after the intravascular administration of iodinated contrast media for diagnostic imaging. Currently, it represents the second cause of hospital-acquired acute kidney injury and is linked to excess morbidity and mortality. One of the most important risk multipliers for(More)
OBJECTIVES To compare the radial versus femoral approach using Angio-Seal for the incidence of access site complications among non-ST-segment elevation acute coronary syndrome patients undergoing invasive strategy. BACKGROUND Arterial access is a major site of complications after invasive coronary procedures. Vascular closure devices provide more comfort(More)
We investigated the relationship of the positivity for Chlamydophila pneumoniae (Cpn) and Mycoplasma pneumonia (Mpn), inflammatory and metabolic markers, and mRNA expression and polymorphisms of the TLR2, TLR4, IL-6 and TNFA genes with acute myocardial infarction (AMI). Two hundred and eighteen individuals (98 AMI and 120 non-AMI) were selected at two(More)
BACKGROUND Diabetes mellitus represents an independent risk factor for contrast-induced acute kidney injury. We report the results of a prespecified substudy of patients with diabetes mellitus included in the Acetylcysteine for Contrast-Induced Nephropathy Trial (ACT), the largest randomized study evaluating the effects of acetylcysteine for the prevention(More)
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