Amanda Bradley-Stewart

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BACKGROUND Influenza virus affects millions of people worldwide each year. More severe infection occurs in the elderly, very young and immunocompromised. In 2009, a new variant of swine origin (influenza A(H1N1)pdm09 virus) emerged that produced severe disease in young healthy adults. OBJECTIVES The aim of this study was to determine whether cytokine(More)
Infection with hepatitis E virus (HEV) can be clinically inapparent or produce symptoms and signs of hepatitis of varying severity and occasional fatality. This variability in clinical outcomes may reflect differences in host susceptibility or the presence of virally encoded determinants of pathogenicity. Analysis of complete genome sequences supports the(More)
Autochonous Hepatitis E (HEV) prevalence has increased in urope in recent years. As well as causing a self-limiting hepatitis, EV can establish chronic infection in the immunocompromised hich can lead to cirrhosis and liver failure, as described by Hassng and others [1–5]. We sought to determine HEV prevalence in a ohort of high-risk patients in Scotland(More)
BACKGROUND Transmitted integrase inhibitor resistance is rare, with only a small number of cases reported world-wide to date. OBJECTIVES The aim of this study was to assess whether transmitted integrase inhibitor resistance has occurred in Scotland and if so, could there be a case for performing genotypic integrase resistance testing at baseline. STUDY(More)
BACKGROUND AND AIMS The majority of influenza infections during the 2012/2013 influenza season in Scotland have been due to influenza A H3N2. We report an outbreak of influenza A H3N2 in a vaccinated population of adults in the Regional Virology Laboratory in Glasgow. This investigation was carried out to confirm the epidemiological link between cases. (More)
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