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- Amélie Servettaz, Claire Goulvestre, +8 authors Frédéric Batteux
- Journal of immunology
- 2009
Systemic sclerosis (SSc) is a connective tissue disorder of great clinical heterogeneity. Its pathophysiology remains unclear. Our aim was to evaluate the relative roles of reactive oxygen species… (More)
- Amélie Servettaz, Philippe Guilpain, +7 authors Luc Mouthon
- Proteomics
- 2008
In order to identify target antigens of anti-endothelial cell (anti-EC) antibodies (AECA) in healthy individuals, we have used a proteomic approach combining 2-DE and immunoblotting. Whole cell… (More)
- Niloufar Kavian, Wioleta Marut, +7 authors Frédéric Batteux
- Arthritis and rheumatism
- 2012
OBJECTIVE
In patients with systemic sclerosis (SSc), activated fibroblasts produce reactive oxygen species (ROS) that stimulate their proliferation and collagen synthesis. By analogy with tumor cells… (More)
- Amélie Servettaz, Philippe Guilpain, +7 authors Frédéric Batteux
- Annals of the rheumatic diseases
- 2007
OBJECTIVES
To investigate the role of reactive oxygen species (ROS) in the development of the various patterns of systemic sclerosis (SSc) and the mechanisms of ROS production by endothelial cells… (More)
- Mathieu C Tamby, Youri Chanseaud, +10 authors Luc Mouthon
- Thorax
- 2005
BACKGROUND
It has previously been shown that IgG antibodies from patients with limited cutaneous systemic sclerosis (SSc) bind to specific microvascular endothelial cell antigens. Since patients with… (More)
Targeting ADAM-17/notch signaling abrogates the development of systemic sclerosis in a murine model.
- Niloufar Kavian, Amélie Servettaz, +10 authors Frédéric Batteux
- Arthritis and rheumatism
- 2010
OBJECTIVE
Systemic sclerosis (SSc) is characterized by the fibrosis of various organs, vascular hyperreactivity, and immunologic dysregulation. Since Notch signaling is known to affect fibroblast… (More)
- Amélie Servettaz, Mathieu C Tamby, +7 authors Luc Mouthon
- Clinical immunology
- 2006
By using a quantitative immunoblotting technique on protein extracts of human macrovascular and microvascular endothelial cells, we have analyzed the self-reactive repertoires of IgG from 20 patients… (More)
- Amélie Servettaz, Philippe Guilpain, Nicolas Tamas, Srini V Kaveri, Luc Camoin, Luc Mouthon
- Autoimmunity reviews
- 2008
Anti-endothelial cell antibodies (AECA) are detectable in a heterogenous group of autoimmune and inflammatory conditions. These antibodies have also been detected in healthy individuals.… (More)
- Christophe Strady, Laurent Andréoletti, Sonia Baumard, Amélie Servettaz, Roland Jaussaud, A. Strady
- Transactions of the Royal Society of Tropical…
- 2009
A multivariate analysis was used to identify factors influencing the immunogenicity of rabies vaccine and to assess the efficacy of booster injections in a cohort of 407 people monitored… (More)
- Wioleta Marut, Niloufar Kavian, +6 authors Frédéric Batteux
- Arthritis and rheumatism
- 2013
OBJECTIVE
Systemic sclerosis (SSc) is characterized by microvascular damage, fibrosis of skin and visceral organs, and autoimmunity. Previous studies have shown that angiotensin II is involved in the… (More)