Amália Cínthia Meneses do Rêgo

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PURPOSE Statins are widely recognized as hypolipemic drugs, but some studies have observed anti-inflammatory and immunomodulatory effects, known as pleiotropic. The aims of this work was to study possible anti-inflammatory effects of simvastatin in abdominal sepsis. Serum pro-inflammatory cytokines and leukocytes count were determined in an experimental(More)
PURPOSE This study explores the potential of the simvastatin to ameliorate inflammation and infection in open infected skin wounds of rats. METHODS Fourteen Wistar rats weighing 285 +/- 12g were used. The study was done in a group whose open infected skin wounds were treated with topical application of simvastatin microemulsion (SIM, n=7) and a second(More)
PURPOSE Many patients with metastatic bone disease have to use radiopharmaceuticals associated with chemotherapy to relieve bone pain. The aim of this study was to assess the influence of docetaxel on the biodistribution of samarium-153-EDTMP in bones and other organs of rats. METHODS Wistar male rats were randomly allocated into 2 groups of 6 rats each.(More)
Biodistribution of technetium-99m pertechnetate after Roux-en-Y gastric bypass (Capella technique) in rats 1 Biodistribuição de tecnécio-99m pertecnetato após desvio gástrico em Y de Roux (técnica de Capella) em ratos ABSTRACT Purpose: The biodistribution of sodium pertechnetate, the most used radiopharmaceutical in nuclear medicine, has not been studied in(More)
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