Alyssa Spector

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Calf lens protein components separated by DEAE chromatography have been related to the crystallins isolated by the new method. Gamma crystallin is the first fraction eluted from the column, folloioed by the beta crystallin components, and then the alpha crystallin subgroup. Since the DEAE separable components could thus be identified as members of the(More)
Congenital pancreatic triglyceride lipase (PNLIP) deficiency is a rare disorder with uncertain genetic background as most cases were described before gene sequencing was readily available. Recently, two brothers with PNLIP deficiency were found to carry a homozygous missense mutation, c.662C>T (p.T221M) in the PNLIP gene (J. Lipid Res. 2014. 55:307-312).(More)
Calf and rabbit lenses cultured in a medium containing a radioactive amino acid incorporate some labeled amino acids into a minor protein fraction, the HL (high labeled) protein, three or four times more rapidly than into any other soluble lens protein. This fraction, isolated by DEAE chromatography, represents about 11 per cent of the total protein but(More)
A review of recent work upon lens proteins suggests that Morners concept of three soluble lens proteins may still be tenable. This conclusion is based upon consideration of physical and chemical studies. Ultracentrifugal investigations of alpha crystallin indicate that it is composed of a number of different-sized aggregates of subunits held together by(More)
F -L re rom the small informal research meetings which were held in New York in the late 1920's, the Association for Research in Vision and Ophthalmology (ARVO) has grown into the predominant scientific eye research organization of this country with more than two thousand members. Early in its development, the association began to honor distinguished(More)
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