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One hundred and two cases of neonatal cancers, representing 2% of all paediatric malignancies, were seen during a 60 year period at The Hospital for Sick Children, Toronto, Canada. The neonatal cancers included neuroblastoma (47%), retinoblastoma (17%), soft tissue sarcoma (12%), central nervous system tumours (9%), leukaemia (8%), and a few cases of Wilms'(More)
BACKGROUND Despite their potential advantages, new coronary angioplasty devices may be associated with more frequent vascular complications than noted after standard balloon angioplasty, theoretically due to the larger sheaths and prolonged periods of anticoagulation required by some of these devices. This study sought to identify the incidence, predictors,(More)
Percutaneous balloon mitral valvulotomy (PBMV) has become an established method of treating symptomatic patients with rheumatic mitral stenosis. PBMV is performed with fluoroscopic guidance alone in most centres. However, even experienced operators can be misled by radiographic anatomic landmarks. Transesophageal echocardiography (TEE) provides high-quality(More)
BACKGROUND Malignant melanoma (MM) is one of the least common types of childhood cancer, accounting for less than 1% of all pediatric malignancies. Neurocutaneous melanosis (NCM) is a rare phakomatosis consisting of congenital abnormal pigmentation of the skin and meninges. The meningeal lesions are particularly prone to malignant change. METHODS The(More)
A questionnaire evaluation was undertaken of feeding methods used by the mothers of 25 neonates with cleft lip and/or palate. Most parents had problems feeding their babies, both with the quantity of food taken and especially with the time taken to feed; even after a period of 2 months over a quarter were still having problems with the quantity of feed and(More)
Percutaneous transvenous balloon mitral valvuloplasty is a well-established alternative to surgical commissurotomy for selected symptomatic patients with rheumatic mitral stenosis. This procedure normally is performed with fluoroscopic guidance; however, even the experienced operator can be misled by radiographic landmarks. The addition of on-line TEE(More)
The fat overload syndrome developed in a 7-yr-old girl receiving total parenteral nutrition with 20% Intralipid. She developed a bleeding disorder characterized by severe hematemesis that appeared to be due to abnormal platelet function associated with platelet phagocytosis of lipid demonstrable by electron microscopy. The platelet defect and bleeding(More)
Exposure of neonates to sound and to mechanical vibration was measured while transferring the neonates to a regional referral unit by ambulance and by rotary wing and fixed wing aircraft. Recordings were made during different phases of each type of transportation and were analyzed later. In the nursery, sound levels ranged from 72 to 74 dBA (A-weighted(More)
Chronic restraint stress alters hippocampal-dependent spatial learning and memory in a sex-dependent manner, impairing spatial performance in male rats and leaving intact or facilitating performance in female rats. Moreover, these stress-induced spatial memory deficits improve following post-stress recovery in males. The current study examined whether(More)
Fifty one infants who were oxygen dependent after treatment for neonatal respiratory disease were entered into a study programme where 100% oxygen was delivered at low flow through a nasal catheter. Thirty five (69%) of the infants were discharged home and the remainder were either discharged to a convalescent hospital or back to their peripheral referring(More)