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  • Mary F. Lopez, Alvydas Mikulskis, +16 authors David A. Fishman
  • Medicine, Chemistry
  • Clinical chemistry
  • 2007 (First Publication: 19 April 2007)
  • BACKGROUND Most cases of ovarian cancer are detected at later stages when the 5-year survival is approximately 15%, but 5-year survival approaches 90% when the cancer is detected early (stage I). ToContinue Reading
  • Alvydas Mikulskis, Dave Yeung, Meena Subramanyam, Lakshmi Amaravadi
  • Biology, Medicine
  • Journal of immunological methods
  • 2011 (First Publication: 1 February 2011)
  • Humanized monoclonal antibody therapeutics are in many ways indistinguishable from the anti-therapeutic/anti-drug antibodies generated in humans. Therefore, immunogenicity assessments to suchContinue Reading
  • Mary F. Lopez, Alvydas Mikulskis, +17 authors Gershon M. Wolfe
  • Medicine, Chemistry
  • Clinical chemistry
  • 2005 (First Publication: 1 October 2005)
  • BACKGROUND Researchers typically search for disease markers using a "targeted" approach in which a hypothesis about the disease mechanism is tested and experimental results either confirm or disproveContinue Reading
  • Jonathan Q. Tran, Ahmed A. Othman, Alvydas Mikulskis, Paul Wolstencroft, Jacob S. Elkins
  • Medicine
  • Clinical pharmacology : advances and applications
  • 2016 (First Publication: 1 February 2016)
  • BACKGROUND Daclizumab high-yield process (DAC HYP), a humanized immunoglobulin G1 monoclonal antibody specific for the α subunit (CD25) of the high-affinity interleukin-2 receptor, has demonstratedContinue Reading
  • Chenwei Liu, Nancy M. Shea, +13 authors Gordon R. Whiteley
  • Medicine, Biology
  • Proteomics
  • 2007 (First Publication: 1 November 2007)
  • Proteomic patterns as a potential diagnostic technology has been well established for several cancer conditions and other diseases. The use of machine learning techniques such as decision trees,Continue Reading