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Oncomirs are microRNAs (miRNA) associated with carcinogenesis and malignant transformation. They have emerged as potential molecular targets for anti-cancer therapy. We hypothesize that grape seed… Continue Reading
It has been proposed that the hemodynamic deterioration associated with heart failure (HF) may be due in part to ongoing loss of viable cardiac myocytes through apoptosis. Hypoxia has been shown to… Continue Reading
Certain formsofextracorporeal circulation exemplified bycardiopulmonary bypassrequire continuous high-dose anticoagulation topreventthromboembolic complications. We hypothesized thatmonocytes may… Continue Reading