Alvaro R. Ramirez

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Codon 72 polymorphism of the tumor suppressor gene TP53 has been associated with a higher risk in the development of several types of cancer. The polymorphism results in a variant protein with either an arginine (CGC) or a proline residue (CCC). The aim of this study was to analyze the association of the TP53 codon 72 polymorphism with the risk of(More)
OBJECTIVE To test the accuracy of predicting life-expectancy (LE) among 19 raters, as the accurate prediction of LE in candidates for definitive therapy for localized prostate cancer is crucial, and little is known of the ability of clinicians to predict LE. SUBJECTS AND METHODS We randomly selected the case-vignettes of 50 patients treated with either(More)
OBJECTIVE To test the hypothesis that individual surgical volume (SV) is an independent predictor of radical prostatectomy (RP) total charges. METHODS We used the Florida State Inpatient Data File. ICD-9 codes 60.5 (RP) and 185 (prostate cancer) identified all men treated with RP for prostate cancer between January 1 and December 31, 1998. Among 1,923,085(More)
OBJECTIVE To examine prostate specific-antigen (PSA) levels and percentage free/total PSA (f/tPSA) distributions as well as digital rectal examination (DRE) profiles in asymptomatic Canadian men with no established prostate cancer diagnosis, as recent data indicate that a man's risk of developing prostate cancer is higher if his baseline PSA level is above(More)
OBJECTIVE The accuracy of 1997 Partin Tables' lymph node invasion (LNI) predictions exhibits important variability in different testing populations. We explored the LNI predictive accuracy in radical prostatectomy (RP) patients from Montreal, Canada. Moreover, we assessed the extent of change in predictive accuracy related to a modification of PSA coding(More)
OBJECTIVES We explored the specific impact of urinary diversion type on HRQOL in men after cystectomy for bladder cancer. Our intent was to provide a basis for the development of a diversion-specific instrument. METHODS We invited 13 ileal conduit and 12 orthotopic urinary diversion (neo-bladder) male patients to several open-ended interviews. We explored(More)
The main event in blood coagulation is the thrombincatalyzed conversion of fibrinogen into fibrin. This singular transformation of a soluble protein into an insoluble polymeric network occurs with faultless precision. Abnormalities of fibrin polymerization can lead to hemorragic and thrombotic disorders. Increased fibrinogen plasma concentration (Fg) and(More)
Mark Wenner is Senior Financial Specialist in the Rural Development Unit. Sergio Navajas is Microenterprise Specialist in the Micro, Small and Medium Enterprise Division. Carolina Trivelli and Álvaro Tarazona are researchers at the Institute for Peruvian Studies (IEP) in Lima, Peru. The authors are grateful for the valuable comments received from Juan(More)
Tor Jansson (torj@iadb.org) is a microfinance specialist in the Micro, Small and Medium Enterprise Division. The author recognizes the valuable comments and suggestions made The views and opinions expressed herein are those of the author and do not necessarily represent the official position of the Inter-American Development Bank. Foreword This paper(More)