Altug Ozcelikkale

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This study aims to characterize and understand the effects of freezing on collagen structures and functionality. Specifically, thermodynamic destabilization of collagen at molecular- and fibril-levels by combination of low temperatures and freezing were experimentally characterized using modulated differential scanning calorimetry. In order to delineate the(More)
Use of numerical solutions to flow phenomena has become increasingly common among non-engineering disciplines such as medical sciences. This increasing interest can be promoted by the ability of solvers to obtain accurate numerical solutions without the need for expertise in some specific subjects such as grid generation or automatic grid adaptation. In(More)
Quality and functionality of engineered tissues are closely related to the microstructures and integrity of their extracellular matrix (ECM). However, currently available methods for characterizing ECM structures are often labor-intensive, destructive, and limited to a small fraction of the total area. These methods are also inappropriate for assessing(More)
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