Altheia Jones-LeCointe

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BACKGROUND Anaemia has been shown in previous studies to be a risk factor for cardiovascular disease in diabetic patients with chronic kidney disorder. This study was aimed to assess the prevalence of anaemia and kidney dysfunction in Caribbean type 2 diabetic patients that have been previously shown to have a high prevalence of the metabolic syndrome. (More)
Biallelic mutations in LEPRE1 result in recessively inherited forms of osteogenesis imperfecta (OI) that are often lethal in the perinatal period. A mutation (c.1080+1G>T, IVS5+1G>T) in African Americans has a carrier frequency of about 1/240. The mutant allele originated in West Africa in tribes of Ghana and Nigeria where the carrier frequencies are 2% and(More)
729 were identical irrespective of whether ["C]-or [3H]-labetalol had been administered to the animals; therefore labetalol is not metabolized by N-dealkylation. The urine samples were concentrated on Amberlite XAD-2 resin, and the metabolites were purified by t.1.c. and paper chromatography. Enzymic hydrolysis, chemical analysis, t.l.c., paper(More)
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