Alpana Ohri

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Antibodies to complement factor H are an uncommon cause of hemolytic uremic syndrome (HUS). Information on clinical features and outcomes in children is limited. In order to explore this we studied a multicenter cohort of 138 Indian children with anti-complement factor H antibody associated HUS, constituting 56% of patients with HUS. Antibody titers were(More)
Several traditional medicines contain potentially toxic heavy metals. Heavy metal poisoning is not an uncommon cause of renal damage, although the diagnosis can be easily missed. We report a case of chronic ingestion of an ayurvedic medicine containing mercury in a 2-year-old girl, resulting in anuric renal failure due to acute interstitial nephritis.
In the scenario of overwhelming bacterial, viral infections and parasitic infestations, rickettsial diseases are an ignored lot. They can present with a myriad of symptoms like fever, headache, rash, meningitis, congestive cardiac failure and shock. They can closely mimic multiple illnesses like meningococcaemia, enteric fever, dengue, leptospirosis and(More)
Smith-Lemli-Opitz syndrome is an autosomal recessively inherited disorder. A severe defect in cholesterol biosynthesis has been identified leading to abnormally low plasma cholesterol levels and elevated levels of the cholesterol precursor 7-dehydrocholesterol, the result of deficiency of 7-dehydrocholesterol reductase. We describe one such child with(More)
Methicillin resistant Staphylococcus aureus (MRSA) meningitis is rarely known to occur in children. We report an 11-year-old girl with fever, headache and vomiting, right hemiparesis with left-sided upper motor neuron facial nerve palsy and bladder incontinence. On investigation, she was found to have MRSA meningitis with an acute left thalamo-corpuscular(More)
This is a randomized, parallel group, active controlled trial to compare the efficacy of intravenouswith oral cyclophosphamide in patients with steroid-resistant nephrotic syndrome (SRNS). Fifty consecutive children with SRNS were biopsied and then randomized to receive either oral cyclophosphamide (OCP) at a dose of 2mg/kg per day for 12 weeks or(More)
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