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A single mammalian cell includes an order of 10(4)-10(5) mRNA molecules and as many as 10(5)-10(6) ribosomes. Large-scale simultaneous mRNA translation induces correlations between the mRNA molecules, as they all compete for the finite pool of available ribosomes. This has important implications for the cell's functioning and evolution. Developing a better… (More)

The asymmetric simple exclusion process (ASEP) is an important model from statistical physics describing particles that hop randomly from one site to the next along an ordered lattice of sites, but only if the next site is empty. ASEP has been used to model and analyze numerous multiagent systems with local interactions including the flow of ribosomes along… (More)

—The asymmetric simple exclusion process (ASEP) is an important model from statistical physics. The model describes particles that hop along an ordered lattice of n sites. The particles hop randomly from one site to the next, but only if the next site is empty. Hence the term simple exclusion. In ASEP with periodic boundary conditions the lattice is closed,… (More)

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