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A mathematical description of the regulation of ATP production in muscle cells is presented whereby the activity of OxP can be calculated as a function of (1) free [ADP] as the substrate and (2) a second driving force ΦΔG (kilojoules per mole) resulting from the difference of free energy ΔG ox,ap (kilojoules per mole)–ΔG ATP,cyt (kilojoules per mole). In(More)
  • A Mader
  • 1988
The balance between protein synthesis and degradation, and between active skeletal muscle cell hypertrophy and atrophy can be described as a function of protein degradation rate by a transcription-translation activation control loop. Transcription activity is presumed to be determined by the concentration of protein-specific fragments (PSF) occurring as(More)
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