Almira L. Hoogesteijn

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We studied whether polychlorinated biphenyls (PCBs) may alter the development of song control brain nuclei in zebra finch (Taeniopygia guttata) offspring of pulse-exposed hens. We orally administered 40 microg of Aroclor 1248 to adult female finches before egg laying. When the progeny were 50 d old, we measured the volumes of the song control nuclei(More)
BACKGROUND Improved characterization of infectious disease dynamics is required. To that end, three-dimensional (3D) data analysis of feedback-like processes may be considered. METHODS To detect infectious disease data patterns, a systems biology (SB) and evolutionary biology (EB) approach was evaluated, which utilizes leukocyte data structures designed(More)
BACKGROUND To extract more information, the properties of infectious disease data, including hidden relationships, could be considered. Here, blood leukocyte data were explored to elucidate whether hidden information, if uncovered, could forecast mortality. METHODS Three sets of individuals (n = 132) were investigated, from whom blood leukocyte profiles(More)
BACKGROUND Diagnostic errors can occur, in infectious diseases, when anti-microbial immune responses involve several temporal scales. When responses span from nanosecond to week and larger temporal scales, any pre-selected temporal scale is likely to miss some (faster or slower) responses. Hoping to prevent diagnostic errors, a pilot study was conducted to(More)
The effects of polychlorinated biphenyls (PCBs) as compounds that may disrupt endocrine activity and, consequently, alter reproductive performance were investigated in altricial zebra finches (Taeniopygia guttata). The breeding performance and breeding cycle of zebra finches differed significantly between nonexposed birds and those experimentally(More)
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