Allison R Edwards

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OBJECTIVE Evaluate intravitreal 0.5 mg ranibizumab or 4 mg triamcinolone combined with focal/grid laser compared with focal/grid laser alone for treatment of diabetic macular edema (DME). DESIGN Multicenter, randomized clinical trial. PARTICIPANTS A total of 854 study eyes of 691 participants with visual acuity (approximate Snellen equivalent) of 20/32(More)
OBJECTIVE To report 3-year outcomes of patients who participated in a randomized trial evaluating 1-mg and 4-mg doses of preservative-free intravitreal triamcinolone compared with focal/grid photocoagulation for treatment of diabetic macular edema. METHODS Eyes with diabetic macular edema and visual acuities of 20/40 to 20/320 were randomly assigned to(More)
PURPOSE To compare the peripapillary retinal nerve fiber layer (RNFL) thickness of sound and amblyopic eyes. DESIGN Prospective observational case series. METHODS SETTING Institutional. STUDY POPULATION Patients with unilateral strabismic, anisometropic, or combined amblyopia. OBSERVATION Fast RNFL analysis with ocular coherence tomography (OCT)(More)
OBJECTIVE To evaluate the effectiveness of treatment of amblyopia in children aged 7 to 17 years. METHODS At 49 clinical sites, 507 patients with amblyopic eye visual acuity ranging from 20/40 to 20/400 were provided with optimal optical correction and then randomized to a treatment group (2-6 hours per day of prescribed patching combined with near visual(More)
PURPOSE To evaluate factors ¶associated with favorable outcomes after vitrectomy for diabetic macular edema. METHODS Data were collected prospectively on 241 eyes undergoing vitrectomy for diabetic macular edema. Multivariate models were used to evaluate associations of 20 preoperative and intraoperative factors with 6-month outcomes of visual acuity and(More)
PURPOSE To report data on the response of previously untreated strabismic amblyopia to spectacle correction. DESIGN Prospective, interventional case series. METHODS Twelve patients with previously untreated strabismic amblyopia were prescribed spectacles and examined at five-week intervals until visual acuity was not improved from the prior visit. (More)
PURPOSE To identify factors associated with the visual acuity outcome after focal/grid photocoagulation for diabetic macular edema (DME) among eyes randomized to the focal/grid photocoagulation treatment group within the Diabetic Retinopathy Clinical Research Network ( trial comparing triamcinolone with focal/grid laser. DESIGN Multicenter,(More)
OBJECTIVE To evaluate the effectiveness of refractive correction alone for the treatment of untreated anisometropic amblyopia in children 3 to <7 years old. DESIGN Prospective, multicenter, noncomparative intervention. PARTICIPANTS Eighty-four children 3 to <7 years old with untreated anisometropic amblyopia ranging from 20/40 to 20/250. METHODS(More)
OBJECTIVE To provide data on the short-term effect of intravitreal bevacizumab for diabetic macular edema (DME). DESIGN Randomized phase II clinical trial. PARTICIPANTS One hundred twenty-one eyes of 121 subjects (109 eligible for analysis) with DME and Snellen acuity equivalent ranging from 20/32 to 20/320. INTERVENTIONS Random assignment to 1 of 5(More)
BACKGROUND To plan a future randomized clinical trial, we conducted a pilot study to determine whether children randomized to near or non-near activities would perform prescribed activities. A secondary aim was to obtain a preliminary estimate of the effect of near versus non-near activities on amblyopic eye visual acuity, when combined with 2 hours of(More)