Allison L. Schure

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Maraviroc (MVC) gels are effective at protecting rhesus macaques from vaginal SHIV transmission, but breakthrough infections can occur. To determine the effects of a vaginal MVC gel on infecting SHIV populations in a macaque model, we analyzed plasma samples from three rhesus macaques that received a MVC vaginal gel (day 0) but became infected after(More)
Myoballs, spherical muscle cell regenerates, have two types of Na+ channels, the adult type with a high sensitivity to the Na+ channel blocker tetrodotoxin (TTX), and the juvenile type with 10 times less TTX sensitivity. The potential dependence of the steady-state inactivation of the Na+ channels (h infinity-curve) was studied in 50 rat myoballs with the(More)
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