Allison Alcivar Hahn

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The inhibitors of apoptosis (IAPs) are critical regulators of apoptosis and other fundamental cellular processes. Many IAPs are RING domain-containing ubiquitin E3 ligases that control the stability of their interacting proteins. However, how IAP stability is regulated remains unclear. Here we report that USP19, a deubiquitinating enzyme, interacts with(More)
Vascular smooth muscle cells from spontaneously hypertensive rats (SHR) were growth stimulated when cocultured with bovine aortic endothelial cells whereas myocytes from normotensive, Wistar Kyoto rats (WKY) were growth inhibited. The responsiveness of cells from the two rat sources to the two homodimeric forms of platelet-derived growth factor (PDGF-AA or(More)
We have investigated whether the polycationic structure of apo B is an important determinant for the recognition of low density lipoprotein (LDL) by putative signalling-coupled/growth receptor(s). Using cultures of human vascular smooth muscle cells (VSMC), the effects of LDL on phosphoinositide (PI) catabolism and DNA synthesis have been compared with(More)
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