Allen J. Flynn

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Pharmacy has an established history of technology use to support business processes. Pharmacy informatics education within doctor of pharmacy programs, however, is inconsistent, despite its inclusion as a requirement in the 2007 Accreditation Council for Pharmacy Education Standards and Guidelines. This manuscript describes pharmacy informatics knowledge(More)
All known guanidino kinases contain a conserved cysteine residue that interacts with the non-nucleophilic eta1-nitrogen of the guanidino substrate. Site-directed mutagenesis studies have shown that this cysteine is important, but not essential for activity. In human muscle creatine kinase (HMCK) this residue, Cys283, forms part of a conserved(More)
The specificity of medication-related alerts must be improved to overcome the pernicious effects of alert fatigue. A systematic comparison of new drug orders to historical orders could improve alert specificity and relevance. Using historical order data from a computerized provider order entry system, we alerted physicians to atypical orders during the(More)
OBJECTIVES To assess pharmacy informatics education, identify current competencies, and develop a foundational set of recommendations. METHODS Accredited pharmacy programs were contacted. Data were collected using a mixed-mode procedure. Didactic and experiential syllabi were analyzed for compliance with informatics competencies in Accreditation Council(More)
David Troiano, B.S.Pharm., M.S.I.A., is Director of Consulting, Dearborn Advisors, Chicago, IL. Michael A. Jones, Pharm.D., is Informatics Pharmacist for Clinical Decision Support, University of Colorado (UC) Hospital, Aurora, and Adjunct Associate Clinical Professor, Skaggs School of Pharmacy and Pharmaceutical Sciences, UC Anschutz Medical Campus, Aurora.(More)
This paper provides a review of some previously identified requirements of a learning health system, a post hoc analysis of narrative artifacts describing a learning health system, and some new potential requirements of a learning health system. Engaging a transdisciplinary group of researchers and health care practitioners, we used a method of group(More)
Recently the crystal structure of creatine kinase from Torpedocalifornica was determined to 2.1 A. The dimeric structure revealed two different forms in the unit cell: one monomer was bound to a substrate, MgADP, and the other monomer was bound to a transition-state analogue complex composed of MgADP, nitrate and creatine. The most striking difference(More)
Computerization is transforming health care. All clinicians are users of health information technology (HIT). Understanding fundamental principles of informatics, the field focused on information needs and uses, is essential if HIT is going to support improved patient outcomes. Informatics education for clinicians is a national priority. Additionally, some(More)
The objective of this minitrack is to contribute to the body of knowledge that helps academics and practitioners to investigate how IT can enable knowledge creation, retention, transfer and application, design, deploy and evaluate advanced knowledge systems, explore and leverage appropriate project management methods and tools for designing and deploying(More)