Allan R. Rutzen

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PURPOSE Vasoactive intestinal peptide (VIP) is expressed by corneal endothelial (CE) cells and is present in the aqueous humor, which bathes CE cells in vivo. This study demonstrated the role of CE cell VIP in maintaining the expression level of a CE differentiation marker, N-cadherin, and the hexagonal cell shape. METHODS To determine the most effective(More)
The Brown-McLean syndrome is defined by corneal edema that involves the peripheral 2.0 to 3.0 mm of cornea, sparing the central cornea. This syndrome is usually associated with previous cataract surgery but has been reported rarely in patients with other predisposing factors such as angle-closure glaucoma or spontaneous lens absorption with iridodonesis. We(More)
In order to study the potential use of ultrasound as a noninvasive system for altering corneal curvature, we used high-density focused ultrasound at a frequency of 4.8 MHz and 7.9 MHz to produce corneal lesions in the rabbit eye. Intensity and duration threshold exposure conditions were determined for the production of minimally visible lesions. Threshold(More)
PURPOSE To present a patient with a prepapillary vascular loop, a congenital anomaly that has been associated with vitreous hemorrhage and retinal vascular occlusion, who underwent refractive surgery. METHODS A 45-year-old man with 2.00 diopters (D) of myopia and a unilateral prepapillary arterial loop presented with an interest in LASIK. After(More)
PURPOSE To assess the prevalence and etiology of blindness and low vision and to assess the prevalence of common eye diseases in central Cambodia. METHODS In this cross-sectional, population-based study, 6,558 residents of Kandal Province, Cambodia were registered, and 5,803 (88.5%) were interviewed and examined. This house-to-house survey was conducted(More)
Data in the present paper demonstrate a significant inhibition in the progress of sugar cataract formation by systemic administration of pyruvate. The formation of the cataract was induced by feeding young rats a diet containing 30% galactose. All animals fed this diet developed nuclear lens opacity by the end of 30 days. This was delayed if the diet and(More)
PURPOSE To demonstrate the presence of vasoactive intestinal pep-tide (VIP)-immunoreactive molecule in the human aqueous humor collected from eyes undergoing either cataract or glaucoma surgeries and to identify them asses of molecules responsible for the VIP immunoreactivity. METHODS Aqueous humor specimens were collected by parencentesis from nine(More)
A flap tear occurred during laser in situ keratomileusis (LASIK) retreatment using a flap-lifting technique in 1 eye of 2 patients 4 to 5 months after the primary procedure. In the first case, the tear occurred in a decentered, standard thickness flap (168 mum) in a location close to the corneal limbus and limbal vessels. In the second case, the tear(More)
This article discusses the newest antibiotics, antivirals, and antifungals and their application in ophthalmology. The literature is reviewed to present the latest research on topical antibiotics, with particular attention to the newest classes of fluoroquinolones, new oral and topical antifungals, and new oral antivirals. Data comparing in vitro(More)
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