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Malaria infection in humans by Plasmodium species is associated with a reduction in haemoglobin levels, frequently leading to anaemia. Plasmodium falciparum causes the most severe and profound anaemia, with a significant risk of death. This cannot be explained simply by the direct destruction of parasitized red blood cells at the time of release of(More)
A bibliography of leukaemias in Africa is presented from 1904 to 1985. The literature is listed chronologically and is classified geographically (north, south, east and west Africa) and by leukaemia type. The epidemiology of leukaemias in Africa is discussed briefly, especially as to the rarity of acute lymphoblastic leukaemia under the age of four years,(More)
Haemoglobin (Hb) AC electrophoretic pattern was found in 0.7% of the population at Garki, Kano State, northern Nigeria, an area where malaria is hyperendemic. Twenty-one Hb.AC subjects at all ages did not differ from the rest of the population in their frequency or density of Plasmodium falciparum, P. malaria or P. ovale infections, nor in their IgM(More)
  • A F Fleming
  • 1989
Major causes of anaemia in pregnancy in tropical Africa are malaria, iron deficiency, folate deficiency and haemoglobinopathies: now there is added also the acquired immune deficiency syndrome (AIDS). Anaemia is often multifactorial, with the different causes interacting in a vicious cycle of depressed immunity, infection and malnutrition. Anaemia(More)
Two hundred Hausa primigravidae at Zaria were divided into five groups in a randomized double-blind trial of antenatal oral antimalarial prophylaxis, and haematinic supplements. Group 1 received no active treatment. Groups 2 to 5 were given chloroquine 600 mg base once, followed by proguanil 100 mg per day. In addition, group 3 received iron 60 mg daily,(More)
BACKGROUND Benzene is a widely distributed environmental contaminant known to cause leukemia, particularly acute nonlymphocytic leukemia, and perhaps other hematologic neoplasms and disorders. Few epidemiologic studies, however, have been able to address relationships between the extent of benzene exposure and the level of risk. PURPOSE A large cohort(More)
ABO and Rhesus blood group data were analysed from 43187 blood donors belonging to 34 ethnic groups, predominantly from northern Nigeria. This is the largest series to be reported on from the whole of West Africa. Group O was found in 46.6% of all those examined, but the numbers varied from 33.13% to 64.35% in different ethnic groups. Group A was found in(More)