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The neuroleptic malignant syndrome is a rare but dangerous complication of treatment with neuroleptics. The aetiology and pathophysiology of the syndrome are reviewed, and a fatal case is presented where both brain and muscle pathology are described. Striking myopathic changes in this case, accompanied by only minimal and non-specific brain abnormalities,(More)
SUMMARY We used an automated recording system and computer analysis to perform hourly QRS subtractions on ECG signals obtained with dipolar leads in 14 patients admitted within 6 hours of the onset of symptoms of acute myocardial infarction (AMI). The resulting changes in QRS time-voltage area were expressed as a difference vector (QRSMD) which was found to(More)
We made continuous electrocardiographic recordings on magnetic tape during 15 episodes of ischemia in five patients with variant angina to determine the characteristics of the QRS changes. Orthogonal leads were used and the electrocardiograms were analyzed visually and by digital computer. Changes were quantified by subtracting baseline electrocardiograms(More)
The risk of instantaneous death due to ventricular fibrillation was compared in resting and exercised dogs. Three weeks before testing, all dogs had bipolar left ventricular stimulating electrodes implanted and a reversible snare was placed around the anterior descending coronary artery. The dogs were randomly assigned to either an exercise (13 dogs) or a(More)
STUDY DESIGN Randomized, single blind, same subject crossover trial. OBJECTIVES To compare the effects of two neurodynamic treatment doses on range of hip flexion (ROM HF) and electromyographic (EMG) activity of semitendinosus, at first onset of pain (P1). METHODS A total of 26 healthy participants without low back or leg pain received each treatment in(More)
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