Alla A Kicha

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The distribution of free sterols, polyhydroxysteroids and steroid glycosides in different body components of the Far-eastern starfish Patiria (=Asterina) pectinifera has been studied. It was shown that free sterol fractions from aboral and oral body walls, gonads, stomach and pyloric ceca contained Delta(7) sterols with a preponderance of(More)
Two novel steroidal 24-O-xylosides, designated as rathbuniosides R(1) (1) and R(2) (2), and the known amurensoside A (3) and 3-O-sulfomarthasterone (4) have been isolated from the starfish Asterias rathbuni. The structures of all the compounds were determined from their spectroscopic data, including one- and two-dimensional NMR methods. The compounds 1 and(More)
The effects of steroid compounds from Pacific Ocean starfishes were studied using cultured neuroblastoma C-1300 cells. Vital observations and examination of silverimpregnated preparations showed that the test substances in a concentration of 2–10 µM stimulate differentiation and improves survival of neuroblastoma cells under adverse conditions (similarly to(More)
Five new polar steroids, polyhydroxysterols 2-5 and the glycoside leviusculoside J (7), were isolated, along with the previously known compounds 1, 6, 8, and 9, from the alcoholic extract of the Far Eastern starfish Henricia leviuscula. The structures of novel compounds were elucidated by interpretation of spectral data (mainly 2D-NMR), and the(More)
Two new steroid glycosides: distolasteroside D6, (24S)-24-O-(β-D-xylopyranosyl)-5α-cholestane-3β,6α,8,15β,16β,24-hexaol, and distolasteroside D7, (22E,24R)-24-O-(β-D-xylopyranosyl)-5α-cholest-22-ene-3β,6α,8,15β,24-pentaol were isolated along with the previously known distolasterosides D1, D2, and D3, echinasteroside C, and(More)
Six new steroidal biglycosides, cariniferosides A-F (1-6), were isolated along with six previously known glycosides, 7-12, from the alcoholic extract of the starfish Asteropsis carinifera. The structures of 1-6 were determined by extensive NMR and ESIMS techniques. The isolated compounds did not show any apparent cytotoxicity in cancer cell lines HCT-116,(More)
A new steroidal glycoside called aphelasteroside E was isolated from the Far-East starfish Aphelasterias japonica. Its structure was proposed as the sodium salt of 26-O-sulfate (25S)-3-O-β-D-xylopyranosyl-5α-cholestan-3β,5,6β,15α,26-pentaol. Two previously known asterosaponins were also isolated. The structures of the isolated compounds were elucidated(More)
Physiologically active steroidal oligoglycosides from starfish (asterosaponins) are known to fulfill protective functions and regulate maturation processes of ova in these animals [1, 2]. In continuation of research on polar steroidal compounds from the Far-Eastern starfish Aphelasterias japonica [3], we studied the asterosaponin fraction from gonads of(More)
Four new sulfated steroidal glycosides (asterosaponins), hippasteriosides A-D (1-4, resp.), were isolated from the alcoholic extract of the Far Eastern starfish Hippasteria kurilensis, collected in the Sea of Okhotsk near Kuril Islands. Compounds 1-4 were determined to contain the same unprecedented hexasaccharide moiety,(More)