Alison L. Smith

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Bimanual movement can increase activity within the stroke-affected hemisphere and may contribute to recovery in some patients. To understand how bimanual learning may aid recovery post-stroke, the present study used EEG to investigate cortical adaptations associated with short-term bimanual training and the behavioral modulations that transfer to unimanual(More)
Barbiturate Protection in Acute Focal Cerebral Ischemia • We have found that anesthetic technique modifies the neurological and pathological sequelae of unilateral middle cerebral artery and internal carotid artery occlusion in dogs. Occlusion was performed in seven groups of six dogs during each of the following anesthetic regimens: light (0.8%) halothane,(More)
Materials and methods: A total of 2467 crossbred barrows and gilts from 339 litters produced in a commercial multiplication herd were randomly allocated to pens by weaning age. Average weaning-age treatments were 15 days (14, 15, and 16 days) and 20 days (19, 20, and 21 days). To evaluate the effect of weaning age on nursery-pig performance, average daily(More)
OBJECTIVE Previous studies have demonstrated that cortical potentials representing motor preparation for visually-cued movements are enhanced following a single session of visually-cued bimanual movement training (BMT). The neuroanatomical sources that contribute to these rapid training-induced adaptations were unclear. To address this, we compared cortical(More)
Barbiturate Protection From Cerebral Infarction in Primates • Baboons were anesthetized with halothane or pentobarbital prior to middle cerebral artery (MCA) occlusion to test the protective effect of barbiturates against stroke in primates. Significantly less infarction was found in animals that received 90 mg per kilogram pentobarbital or more than(More)
Localized edema follows the freezing of a small area of cerebral cortex. Effects of five subsequent hours of anesthesia on this edema were studied in six groups of six dogs each. Six anesthetic techniques were studied. In six additional "awake" dogs, anesthesia (halothane) was discontinued immediately after the lesion was made. Eight control dogs received(More)