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This paper evaluates automatic extraction of ten named entity classes from a 19th century newspaper, the Civil War years of the <i>Richmond Times Dispatch</i>, digitized with IMLS support by the University of Richmond. This paper analyzes success with ten categories of entities prominent in these newspapers and the particular problems that these classes of(More)
OBJECTIVE To investigate the Australian public's expectations, concerns and willingness to accept vaccination with the pandemic (H1N1) 2009 influenza vaccine. DESIGN, SETTING AND PARTICIPANTS A computer-assisted telephone interview survey was conducted between 20 August and 11 September 2009 by trained professional interviewers to study issues relating to(More)
During development of the central nervous system, the transition from progenitor maintenance to differentiation is directly triggered by a lengthening of the cell cycle that occurs as development progresses. However, the mechanistic basis of this regulation is unknown. The proneural transcription factor Neurogenin 2 (Ngn2) acts as a master regulator of(More)
Inhibitory interneurons play important roles in neuronal circuits, but the synaptic mechanisms that regulate excitatory input onto interneurons remain to be fully understood. We show that ATP-gated presynaptic P2X2 channels facilitate excitatory transmission onto stratum radiatum interneurons but not onto CA1 pyramidal neurons. ATP released endogenously(More)
  • Lesley A Smith, Victoria R Cornelius, Christopher J Plummer, Gill Levitt, Mark Verrill, Peter Canney +1 other
  • 2010
BACKGROUND We conducted a systematic review and meta-analysis to clarify the risk of early and late cardiotoxicity of anthracycline agents in patients treated for breast or ovarian cancer, lymphoma, myeloma or sarcoma. METHODS Randomized controlled trials were sought using comprehensive searches of electronic databases in June 2008. Reference lists of(More)
This paper describes several incunabular assumptions that impose upon early digital libraries the limitations drawn from print, and argues for a design strategy aimed at providing customization and person-alization services that go beyond the limiting models of print distribution, based on services and experiments developed for the Greco-Roman collections(More)
BACKGROUND Snake bite is a neglected public health problem in the world and one of the major causes of mortality and morbidity in many areas, particularly in the rural tropics. It also poses substantial economic burdens on the snake bite victims due to treatment related expenditure and loss of productivity. An accurate estimate of the risk of snake bite is(More)
Recent studies using interleukin (IL)-4-deficient animals have highlighted the existence of IL-4-independent immunoglobulin (Ig)E induction. We have established transgenic mice expressing IL-13 from a transgene comprising a genomic fragment containing the IL-13 gene and the human CD2 locus control region. The transgenes were expressed in lymphoid tissues(More)
One of the principle ways in which reef building corals are likely to cope with a warmer climate is by changing to more thermally tolerant endosymbiotic algae (zooxanthellae) genotypes. It is highly likely that hosting a more heat-tolerant algal genotype will be accompanied by tradeoffs in the physiology of the coral. To better understand one of these(More)