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BACKGROUND Concerns regarding the use of antipsychotic medication in secondary care suggested an examination of primary care prescribing. AIM To audit and intervene in the suboptimal prescribing of antipsychotic drugs to primary care patients. DESIGN OF STUDY Cross-sectional prevalence: subsequent open treatment intervention. SETTING Seven of the 29(More)
A number of presynaptic markers are compromised in the dopaminergic neurons of aged Sprague-Dawley rats (22 months old) compared with young rats (3 months old). Indeed, in the striatum of the aged rats there is a diminished capacity to transport dopamine (DA), to bind the dopamine transporter (DAT) marker mazindol, to bind the vesicular monoamine(More)
Designing effective home healthcare technologies is a complex task. In order to succeed, it is important to look beyond purely technology-driven solutions and to develop technologies and services that are flexible and reflect a sensitive understanding of the diverse users of such systems. The key contribution of this paper is to introduce 15 empirically(More)
Cultural probes are a design research method, which has gained prominence for being particularly suited to conducting research on sensitive topics and in personal contexts. This paper reports the methodological process of designing and deploying cultural probes to investigate the meaning of independence for older adults. We describe the rationale behind the(More)
Maintaining good hydration is crucial for adequate physical and mental performance for all human beings. In this paper we present SPLASH, an Android app that enables users to set daily goals and to keep track of their liquid intake through a combination of smart-phone NFC technology and NFC-tagged cups. We conducted several experiments to verify the(More)
Self-report underpins our understanding of falls among people with Parkinson's (PwP) as they largely happen unwitnessed at home. In this qualitative study, we used an ethnographic approach to investigate which in-home sensors, in which locations, could gather useful data about fall risk. Over six weeks, we observed five independently mobile PwP at high risk(More)