Alison Bevan

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Modern advances in computers have fueled parallel advances in imaging technologies. The improvements in imaging have in turn allowed a higher level of complexity to be incorporated into radiotherapy treatment planning systems. As a result of these changes, the delivery of radiotherapy evolved from therapy designed based primarily on plain (two dimensional)(More)
PURPOSE Resection margin status is one of the most significant factors for local recurrence in patients with ductal carcinoma in situ (DCIS) treated with breast-conserving surgery with or without radiation. However, its impact on chest wall recurrence in patients treated with mastectomy is unknown. The purpose of this study was to determine chest wall(More)
Eleven mild atopic asthmatic patients were exposed for 6 h, in randomized order, to air, 100 ppb O3, 200 ppb NO2, and 100 ppb O3 + 200 ppb NO2, followed immediately by bronchial allergen challenge. Subsequently 10 of these patients were exposed for 3 h to air, 200 ppb O3, 400 ppb NO2, and 200 ppb O3 + 400 ppb NO2, followed immediately by bronchial allergen(More)
Three different types of bivalent influenza virus vaccine, a whole virus, an aqueous-surface-antigen vaccine and an adsorbed-surface-antigen vaccine were tested at three dosage levels in volunteers primed with respect to only one of the haemagglutinin antigens present in the vaccines. The local and systemic reactions to all three vaccine types were mild in(More)
At present influenza vaccines are standardized on their haemagglutinin content only. Recently it has been shown that both neuraminidase and haemagglutinin antibodies are important in providing protection against the influenza virus. We have, therefore, developed an automated neuraminidase assay, based on the enzymic method of Kendal, but modified to(More)
PURPOSE To investigate the planning efficiency and dosimetric characteristics of hybrid direct aperture optimized (hDAO) intensity-modulated radiotherapy (IMRT) compared with forward planning (FP)-IMRT for whole breast irradiation with two tangential beams. METHODS AND MATERIALS A total of 15 patients with left-sided breast cancer, categorized with three(More)
The development of novel technologies for the safe and effective delivery of radiation is critical to advancing the field of radiation oncology. The Emerging Technology Committee of the American Society for Therapeutic Radiology and Oncology appointed a Task Group within its Evaluation Subcommittee to evaluate new electronic brachytherapy methods that are(More)
A modified single-radial-haemolysis (SRH) test for measurement of antibody to influenza virus neuraminidase (NA) is described. The test requires treatment of sheep erythrocytes with butanol to increase sensitivity. In comparative assays, SRH was found to be more sensitive than the conventional neuraminidase-inhibition test. The SRH test was reproducible,(More)
The effect of various factors on the reproducibility of neuraminidase and NI antibody assays has been investigated. These factors include the substrate, strain of virus, nature of virus, i.e. whole, subunit or recombinant, temperature and pH. In assaying antibody levels the challenge virus should be standardized by a method other than optical density. It is(More)
Results: • There were no noticeable effects of the environmental conditions (choice of diluents, temperature or blue light phototherapy) on the physical or chemical compatibility of the drug mixtures. • The precipitation observed in some of the incompatible combinations has been established to be due to either a change in pH that is incompatible with the(More)
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