Aline de Conti

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Summary To determine normal levels of transepidermal water loss (TEWL), capacitance and sebum according to different sex and age groups, 93 healthy subjects were studied at 14 different anatomical locations with three different instruments: the Evaporimeter EP 1, the Corneometer CM 820, and the Sebumeter SM 810, evaluating respectively the transepidermal(More)
Running Title: Chemopreventive activities of geranylgeraniol and β-ionone. Abstract Chemopreventive activities of the isoprenoids geranylgeraniol (GGO) and β-ionone (BI) were evaluated during initial phases of hepatocarcinogenesis. Rats received daily during 7 weeks 8 or 16 mg/100 g body weight GGO (GGO8 and GGO16 groups) or BI (BI8 and BI16 groups), or(More)
Chemopreventive activities of the isoprenoids geranyl-geraniol (GGO) and b-ionone (BI) were evaluated during initial phases of hepatocarcinogenesis. Rats received 8 or 16 mg/100 g body wt GGO (GGO8 and GGO16 groups) or BI (BI8 and BI16 groups), or only corn oil (CO group, controls) daily for 7 weeks. Incidence (%) and the mean number of visible hepatocyte(More)
Furan is a significant food contaminant and a potent hepatotoxicant and rodent liver carcinogen. The carcinogenic effect of furan has been attributed to genotoxic and non-genotoxic, including epigenetic, changes in the liver; however, the mechanisms of the furan-induced liver tumorigenicity are still unclear. The goal of the present study was to investigate(More)
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