Aline Meyer Rosa

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Procedures for the preparation of high- and low-salt Triton insoluble cytoskeletal fractions from rat brain suitable for studying in vitro phosphorylation by endogenous kinases and phosphatases are described. The high-salt Triton insoluble cytoskeletal fraction is enriched in neurofilament subunits (NF-H, NF-M and NF-L), vimentin and glial fibrillary acidic(More)
Recently, rapid and transient cardiac pacing was shown to induce preconditioning in animal models. Whether the electrical stimulation per se or the concomitant myocardial ischemia affords such a protection remains unknown. We tested the hypothesis that chronic pacing of a cardiac preparation maintained in a normoxic condition can induce protection. Hearts(More)
In the current study we investigated the effect of the branched-chain alpha-keto acids (BCKA) co-ketoisocaproic (KIC), alpha-keto-beta-methylvaleric (KMV), and alpha-ketoisovaleric (KIV) acids, which accumulate in maple syrup urine disease (MSUD), on the in vitro uptake of [3H]glutamate by cerebral cortical slices from rats aged 9, 21, and 60 days of life.(More)
Resumo A isquemia intestinal é um problema clínico que pode levar a alterações morfológicas nos neurônios entéricos. Esse estudo analisou os efeitos da isquemia/reperfusão (I/R-i) em neurônios imunorreativos ao receptor P2X 2 e as classes de neurônios no plexo mioentérico do íleo de ratos. A isquemia intestinal foi obtida pela oclusão da artéria mesentérica(More)
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