Aline Ketefian

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Members of the forkhead box O1 (FOXO) family of transcription factors are expressed in granulosa cells during various stages of follicle development, and evidence from rodent and other model systems suggests that they may be involved in regulating follicular activation and oocyte maturation. In this report, we show that FOXO1, FOXO3, and FOXO4 are expressed(More)
OBJECTIVE To evaluate genes involved in androgen receptor (AR) signaling as candidate genes for polycystic ovary syndrome (PCOS). DESIGN Two groups of women with PCOS and control women (discovery and replication cohorts), were genotyped for single-nucleotide polymorphisms (SNPs) in eight genes for AR chaperones and co-chaperones: HSPA1A, HSPA8, ST13,(More)
OBJECTIVE • To determine trends in male reproductive surgeries. MATERIALS AND METHODS • A database analysis was performed using the Healthcare Cost and Utilization Project databases from 1988, 1992 and 1998-2002. SAS statistical software was used to estimate the total numbers of reproductive surgeries and their variances for each year. RESULTS • The(More)
To determine the expression of SMAD transcripts in human granulosa cells. Luteinized mural granulosa cells were harvested from forty women undergoing oocyte retrieval, and RNAs were isolated. SMAD expression levels were determined by polymerase chain reaction (PCR) and quantitative real-time PCR (q-RTPCR). SMAD1-7 and 9 are expressed in human granulosa(More)
OBJECTIVE To determine trends in female reproductive surgery volume. DESIGN Database analysis using the Healthcare Cost and Utilization Project databases from 1988, 1992, 1998, and 2002. SETTING Academic medical center. PATIENT(S) All patients who underwent reproductive surgeries using United States community hospital discharge data and inpatient and(More)
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