Alicia Martín

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BACKGROUND Tolerance to collagen structures has been shown to inhibit the progression of autoimmune scleroderma and rheumatoid arthritis. More recently, tolerance induction to collagen type V (colV) in experimental models of lung transplantation was shown to ameliorate the complex pathology known as "chronic rejection." The link between colV autoimmunity(More)
The regulation of the activity of brain monoaminergic systems has been the focus of attention of many studies since the first antidepressant drug emerged 50 years ago. The search for novel antidepressants is deeply linked to the search for fast-acting strategies, taking into account that 2-4 weeks of treatment with classical antidepressant are required(More)
The omentum is a sheet-like tissue attached to the greater curvature of the stomach and contains secondary lymphoid organs called milky spots. The omentum has been used for its healing potential for over 100 years by transposing the omental pedicle to injured organs (omental transposition), but the mechanism by which omentum helps the healing process of(More)
BACKGROUND Interstitial lung disease encompasses a diverse group of chronic lung conditions characterised by distressing dyspnoea, fatigue, reduced exercise tolerance and poor health-related quality of life. Exercise training is one of the few treatments to induce positive changes in exercise tolerance and symptoms, however there is marked variability in(More)
IL-2 is a growth factor for activated T cells and is required for maintenance of naturally arising regulatory T cells (nTregs). Mice defective in IL-2/IL-2 receptor signaling pathways have impaired nTregs and suffer from lymphoproliferative disorders, suggesting that IL-2 is present and functional in healthy animals. However, the cellular source of IL-2 is(More)
OBJECTIVE To evaluate the inter-rater and intra-rater reliability of the hand held dynamometer in measuring muscle strength in people with interstitial lung disease (ILD). DESIGN Test retest reliability of hand-held dynamometry for elbow flexor and knee extensor strength between two independent raters and two testing sessions. SETTING Physiotherapy(More)
BACKGROUND Uncertainty exists regarding the clinical relevance of exercise training across the range of interstitial lung diseases (ILDs). OBJECTIVE To establish the impact of exercise training in patients with ILDs of differing aetiology and severity. METHODS 142 participants with ILD (61 idiopathic pulmonary fibrosis (IPF), 22 asbestosis, 23(More)
s of the XXV World Congress of Psychiatric Genetics (WCPG): Oral Abstracts Saturday, October 14, 2017 Saturday Afternoon Oral Session: Schizophrenia 1:30 p.m. 3:00 p.m. 1. USING GENETIC DIVERSITY FROM EAST ASIA TO IMPROVE THE BIOLOGICAL INSIGHT INTO SCHIZOPHRENIA Hailiang Huang, Max Lam n, Chia-Yen Chen, Alicia Martin, Zhiqiang Li, Stephan Ripke, Michael(More)
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