Enantioselective Rh-catalyzed hydrogenation of N-formyl dehydroamino esters with monodentate phosphoramidite ligands.
- L. Panella, Alicia Marco Aleixandre, A. Minnaard
- ChemistryJournal of Organic Chemistry
- 3 March 2006
A highly convenient multigram scale one step synthesis of methyl 2-(formamido)acrylate was developed and the versatility of the formyl protection was established by its removal under mild conditions.