Alicia Kelley

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The molecular chaperone HSP90 aids the maturation of a diverse but select set of metastable protein clients, many of which are key to a variety of signal transduction pathways. HSP90 function has been best investigated in animal and fungal systems, where inhibition of the chaperone has exceptionally diverse effects, ranging from reversing oncogenic(More)
The in vitro adsorption and coadsorption of acetaminophen and N-acetylcysteine using simulated gastric (pH 1.2) and intestinal (pH 7.0) conditions were examined for a range of charcoal-to-drug ratios between 1 and 7. Although both substances were adsorbed by the activated carbon, the adsorption of acetaminophen was greater than that of N-acetylcysteine for(More)
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