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Phytochemical profile and anticholinesterase and antimicrobial activities of supercritical versus conventional extracts of Satureja montana.
A comparison between conventional and alternative extraction methods to assess the best option to obtain bioactive compounds and the great potential of S. montana volatile supercritical fluid extract for the growth control and inactivation of Bacillus subtilis and Bacillus cereus is reported. Expand
Antihyperglycaemic and protective effects of flavonoids on streptozotocin–induced diabetic rats
Almost all the tested compounds effectively protected the liver and kidneys against STZ‐induced damage in rats, and significantly lowered the blood glucose levels of diabetic animals. Expand
Supercritical, ultrasound and conventional extracts from carob (Ceratonia siliqua L.) biomass: Effect on the phenolic profile and antiproliferative activity
Abstract A new approach to the extraction of bioactive phenolic compounds from carob kibbles has been proposed. Carob pulp kibbles, a by-product of the carob bean gum production, were subject toExpand
Phenolic composition and antioxidant activity of Rocha pear and other pear cultivars – A comparative study
Associacao Nacional de Produtores de Pera Rocha; Fundacao para a Ciencia e Tecnologia (FCT)
Bioactivity studies and chemical profile of the antidiabetic plant Genista tenera.
The n-butanol extract, where 21 monoglycosyl and 12 diglycosyl flavonoids were detected, significantly lowered blood glucose levels, bringing them to normal values after 15 days of treatment, the first report on antidiabetic activity of genus Genista. Expand
In vitro antioxidant and anti-inflammatory properties of Limonium algarvense flowers' infusions and decoctions: A comparison with green tea (Camellia sinensis).
Under the experimental conditions, infusions and decoctions of L. algarvense flowers had similar or higher antioxidant and anti-inflammatory properties than green tea, and thus, may be useful for alleviating symptoms associated with oxidative and inflammatory-related diseases. Expand
Non-toxic Salvia sclareoides Brot. extracts as a source of functional food ingredients: Phenolic profile, antioxidant activity and prion binding properties
Abstract Salvia sclareoides is an aromatic herb native to Portugal, of which phenolic content (Folin–Ciocalteau method), chemical profile (HPLC/DAD), antioxidant activity (DPPH, β-carotene/linoleicExpand
Natural compounds against Alzheimer's disease: molecular recognition of Aβ1-42 peptide by Salvia sclareoides extract and its major component, rosmarinic acid, as investigated by NMR.
NMR characterization of the interaction of Salvia sclareoides extract and that of its major component, rosmarinic acid, with Aβ1-42 peptide, whose oligomers have been described as the most toxic Aβ species in vivo sheds light on the structural determinants of ros marinic acid-Aβ1 -42 oligomers interaction, thus allowing the elucidation of its mechanism of action. Expand
Liquid chromatography-diode array detection-electrospray ionisation mass spectrometry/nuclear magnetic resonance analyses of the anti-hyperglycemic flavonoid extract of Genista tenera. Structure
The anti-hyperglycemic flavonoid extract obtained from Genista tenera was first studied by liquid chromatography (LC)-diode array detection (DAD) which showed the presence of two major compounds, one of them was identified as genistein-7-O-glucoside and the structure of the unknown major compound was elucidated. Expand
Molecular recognition of rosmarinic acid from Salvia sclareoides extracts by acetylcholinesterase: a new binding site detected by NMR spectroscopy.
The combination of the NMR spectroscopy based data with molecular modelling has permitted us to detect a new binding site in AChE, which could be used for future drug development. Expand